Her familyconfirmed her death to ABC 7 News.

Harper was diagnosed with an incurable form of brain cancer in 2013.

That same year, Harper posed for aPEOPLE cover storyunder a headline that read, Brave Goodbye.

Tower Cancer Research Foundation’s Tower Of Hope Gala - Arrivals

Credit: Paul Archuleta/FilmMagic

And yet she defied the odds.

She was eliminated in week 4.

I am confronting these hurdles with my usual enthusiasm and love of life.

LOS ANGELES - JANUARY 1: The Mary Tyler Moore Show: Valerie Harper who portrays Rhoda Morgenstern. Image dated 1971. (Photo by CBS via Getty Images)

CBS via Getty Images

In recent years, Harper provided her voice talents to numerous parts onThe SimpsonsandAmerican Dad.

Harpers survivors include her second husband, Tony Cacciotti, and their daughter, Cristina Cacciotti.